Searchable abstracts of presentations at key conferences in endocrinology

ea0019p249 | Pituitary | SFEBES2009

Exposure to a cocktail of environmental chemicals in sewage sludge: effects on foetal and post pubertal pituitary gonadotrophs in sheep

Bellingham M , McNutt CRE , Fowler PA , Rhind SM , Cotinot C , Sharpe RM , Evans NP

It has been hypothesised that the hypothalamo–pituitary gland complex is a prime target through which environmental chemicals may alter reproductive physiology. The aim of this study was to investigate whether exposure to an environmentally relevant mix of chemicals during in utero and post-natal development can alter pituitary function. Pituitary glands were collected from 110 day-old foetuses (8 control and 8 treated) and 18 month old, post-pubertal sheep (8 cont...